Sight Sciences Clinical Publications

Glaucoma Clinical Publications

Overview of studies from Glaucoma Clinical Publications
Study Name	Clinical Article/Poster Name	Lead Author's Name	Published Date	Publication	Publisher
	Standalone canaloplasty and trabeculotomy using the OMNI surgical system: a subgroup analysis from the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight)	Pyfer, Mark F	11/2025	Clinical Ophthalmology
Orion 2	Viscodilation of Schlemm’s Canal and Trabeculotomy for Reducing Intraocular Pressure and Medication Use in Pseudophakic Eyes	Olander, Kenneth	10/2025	Journal of Cataract and Refractive Surgery
Orion 2	Ab Interno Minimally Invasive Glaucoma Surgery Effectiveness in Black Patients: IRIS Registry® Study	Mbagwu, Michael	09/2025	Journal of Glaucoma
Meta Analysis	Systematic review and meta-analysis of the clinical effectiveness, safety, humanistic and economic burden of the OMNI® surgical system and its predecessors.	Obeda Kailani	09/2025	European Journal of Ophthalmology	SAGE Publishing
Meta Analysis	Standalone Canaloplasty and Trabeculotomy Using the OMNI Surgical System in Patients with Open-Angle Glaucoma: A Systematic Review and Meta-analysis.	Daniel Zhu	08/2025	Journal of Glaucoma	Wolters Kluwer
	Ab Interno Canaloplasty and Trabeculotomy Outcomes for Mild, Moderate, and Advanced Open-Angle Glaucoma: A ROMEO Analysis	Dickerson, Jaime Jr	05/2024	Clinical Ophthalmology	Dove Press
IRIS Registry	Ab Interno Minimally Invasive Glaucoma Surgery Combined with Cataract Surgery and Cataract Surgery Alone: IRIS® Registry Study	Mbagwu, Michael	04/2024	AJO International	Dove Press
GEMINI 36-Month	36-Month Outcomes from the Prospective GEMINI Study: Canaloplasty and Trabeculotomy Combined with Cataract Surgery for Patients with Primary Open-Angle Glaucoma	Greenwood, Michael	12/2023	Clinical Ophthalmology	Dove Press
	Real-World Outcomes of Canaloplasty and Trabeculotomy Combined with Cataract Surgery in Eyes with All Stages of Open-Angle Glaucoma	Yadgarov, Arkadiy	09/2023	Clinical Ophthalmology	Dove Press
ROMEO 24-Month	Canaloplasty and Trabeculotomy with the OMNI System in Patients with Open-Angle Glaucoma: Two-Year Results from the ROMEO Study	Williamson, Blake	04/2023	Clinical Ophthalmology	Dove Press
	Long-term effect of canaloplasty on intraocular pressure and use of intraocular pressure-lowering medications in patients with open-angle glaucoma	Ondrejka, Simon	12/2022	Journal of Cataract & Refractive Surgery	Wolters Kluwer
TREY	Canaloplasty and trabeculotomy with the OMNI® surgical system in OAG with prior trabecular microbypass stenting	Terveen, Daniel	10/2022	International Ophthalmology	Springer
ROMEO 2	A Multicenter 12-Month Retrospective Evaluation of Canaloplasty and Trabeculotomy in Patients with Open-Angle Glaucoma: The ROMEO 2 Study	Murphy, James	09/2022	Clinical Ophthalmology	Dove Press
	Short-Term Efficacy of Combined ab Interno Canaloplasty and Trabeculotomy in Pseudophakic Eyes with Open-Angle Glaucoma	Bleeker, Adam	07/2022	Clinical Ophthalmology	Dove Press
GEMINI 12-Month	Canaloplasty and Trabeculotomy Combined with Phacoemulsification for Glaucoma: 12-Month Results of the GEMINI Study	Gallardo, Mark	04/2022	Clinical Ophthalmology	Dove Press
GEMINI	Suppression of Diurnal (9AM–4PM) IOP Fluctuations with Minimally Invasive Glaucoma Surgery: An Analysis of Data from the Prospective, Multicenter, Single-Arm GEMINI Study	Pyfer, Mark	09/2021	Clinical Ophthalmology	Dove Press
	Standalone Trabeculotomy and Viscodilation of Schlemm’s Canal and Collector Channels in Open-Angle Glaucoma Using the OMNI Surgical System: 24-Month Outcomes	Klabe, Karsten	07/2021	Clinical Ophthalmology	Dove Press
ROMEO 12-Month (Combo)	Canaloplasty and trabeculotomy ab interno with the OMNI system combined with cataract surgery in open-angle glaucoma: 12-month outcomes from the ROMEO study	Hirsch, Louis	07/2021	Journal of Cataract & Refractive Surgery	Wolters Kluwer
ROMEO 12-Month (Standalone)	Canaloplasty and Trabeculotomy with the OMNI System in Pseudophakic Patients with Open-Angle Glaucoma: The ROMEO Study	Vold, Steven	2021 Mar-Apr	Ophthalmology Glaucoma	Elsevier
	Clinical Results of Ab Interno Canaloplasty in Patients with Open-Angle Glaucoma	Hughes, Trevor	10/2020	Clinical Ophthalmology	Dove Press
	Circumferential Viscodilation Ab Interno Combined with Phacoemulsification for Treatment of Open-Angle Glaucoma: 12-Month Outcomes	Tracer, Nathaniel	05/2020	Clinical Ophthalmology	Dove Press
	Viscodilation of Schlemm canal and trabeculotomy combined with cataract surgery for reducing intraocular pressure in open-angle glaucoma	Brown, Reay	04/2020	Journal of Cataract & Refractive Surgery	Wolters Kluwer

Ocular Surface Clinical Publications

Overview of studies from Ocular Surface Clinical Publications
Study Name	Clinical Article/Poster Name	Lead Author's Name	Published Date	Publication	Publisher
Cost Utility Analysis	TearCare system versus cyclosporine ophthalmic emulsion for the treatment of moderate-to-severe meibomian gland disease associated dry eye disease in the United States: a cost-utility analysis	Lighthizer, Nathan OD	07/2025	Expert Review of Pharmacoeconomics & Outcomes Research	Taylor & Francis
SAHARA	Durability of the TearCare treatment effect in subjects with dry eye disease: Stage 3 of the Sahara randomized controlled trial	Hovanesian, John MD	07/2025	Optometry and Vision Science (Journal of the American Academy of Optometry)	Wolters Kluwer
	Budget impact analysis (BIA) of the TearCare System for the treatment of meibomian gland dysfunction (mgd)-associated dry eye disease (DED) in the United States (US)	Chester, Thomas	10/2024	Expert Review of Ophthalmology	Taylor & Francis & Informa UK Limited, trading as Taylor & Francis Group
	Impact of TearCare on Reading Speed in Patients with Dry Eye Disease	Feng, Yilin	10/2024	Clinical Ophthalmology	Dove Press
SAHARA	Improved signs and symptoms of dry eye disease for Restasis® patients following a single TearCare® treatment: phase 2 of the SAHARA study	Ayres, Brandon D	05/2024	Clinical Ophthalmology	Dove Press
SAHARA	A Randomized, Controlled Trial Comparing Tearcare® and Cyclosporine Ophthalmic Emulsion for the Treatment of Dry Eye Disease (SAHARA).	Ayres, Brandon D	12/2023	Clinical Ophthalmology	Dove Press
	Localized Heat Treatment for Meibomian Gland Dysfunction: A Single-Center Retrospective Analysis of Efficacy over Time	Chester, Thomas	09/2023	Optometry and Vision Science	Wolters Kluwer
OLYMPIA	A Comparison of TearCare and Lipiflow Systems in Reducing Dry Eye Disease Symptoms Associated with Meibomian Gland Disease	Holland, Edward	08/2022	Clinical Ophthalmology	Dove Press
OLYMPIA	TearCare for the Treatment of Meibomian Gland Dysfunction in Adult Patients with Dry Eye Disease: A Masked Randomized Controlled Trial	Gupta, Preeya	09/2021	Cornea	Wolters Kluwer
	A Single-center Retrospective Trial of a Blink-assisted Eyelid Device in Treating the Signs and Symptoms of Dry Eye	Chester, Tom	06/2021	Optometry and Vision Science	Lippincott Williams & Wilkins
CHEETAH	A Prospective, Post-Market, Multicenter Trial (CHEETAH) Suggested TearCare System as a Safe and Effective Blink-Assisted Eyelid Device for the Treatment of Dry Eye Disease	Karpecki, Paul	12/2020	Clinical Ophthalmology	Dove Press
	TearCare System Extension Study: Evaluation of the Safety, Effectiveness, and Durability Through 12 Months of a Second TearCare Treatment on Subjects with Dry Eye Disease	Badawi, David	01/2019	Clinical Opthalmology	Dove Press
	A Novel System, TearCare for the Treatment of the Signs and Symptoms of Dry Eye Disease	Badawi, David	04/2018	Clinical Opthalmology	Dove Press